Sohrab Shah, PhD

Sohrab Shah, PhD

BC Cancer Agency Vancouver Center
Vancouver, BC, Canada

Dr. Sohrab Shah is an Associate Professor in the Departments of Pathology and Computer Science, University of British Columbia and is a Scientist at the BC Cancer Agency. He is the recipient of a Canada Research Chair in Computational Cancer Genomics, a Terry Fox New Investigator Award, and is a Michael Smith Foundation for Health Research Career Investigator. He is also honoured to be the recipient of the UBC Killam Research Prize, Applied Science, Sciences Junior Category. Dr. Shah’s work focuses on characterization of cancer genomes for determination of pathogenic driver mutations in cancer subtypes and measuring and quantifying tumour evolution. His work is in the field of computational cancer genomics and involves development of statistical models and machine learning algorithms to interpret next generation sequence data for defining mutational landscapes and quantifying clonal evolution in ovarian and breast cancers. His recent work describing new cancer genes in ovarian cancer has been published in the New England Journal of Medicine and his work describing mutational evolution in breast cancer has been featured in Nature.

Dr. Shah holds Bachelor’s degrees in Biology (from Queen’s University) and Computer Science (from the University of British Columbia). He worked as a Software Developer at the Centre for Molecular Medicine and Therapeutics Bioinformatics Core, and was Chief, High Throughput Bioinformatics at the UBC Bioinformatics Centre, before obtaining a Masters degree and Ph.D. in Computer Science and Bioinformatics from the University of British Columbia in 2008 studying machine learning for cancer genomics with Dr. Kevin Murphy. Dr. Shah performed his postdoctoral research in the laboratories of Drs. Sam Aparicio and David Huntsman exploring mutational landscapes of breast and ovarian cancers using next generation sequencing technology at the BC Cancer Agency before starting his own research group at the Agency in 2010.

Dr. Shah has co-authored >75 publications that have attracted 10,935 citations (H-index 44, i10-index 64). He has published in such high impact journals as: New England Journal of Medicine, Nature, Nature Genetics, Nature Methods, Genome Research, Nature Communications, Genome Biology and Blood.