Shimon Sakaguchi, MD, PhD

Shimon Sakaguchi, MD, PhD

Osaka University
Osaka, Japan

Shimon Sakaguchi is a Professor at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan. He is an immunologist recognized particularly for his discovery of regulatory T cells, an indispensable constituent of the immune system for the maintenance of immune self-tolerance and homeostasis. Sakaguchi obtained an M.D. in 1976 and a Ph.D. in 1982 from Kyoto University, Japan, where he was trained as a pathologist and immunologist. After performing postdoctoral studies at Johns Hopkins University and Stanford University as a Lucille P. Markey Scholar, he served as an Assistant Professor in the Department of Immunology at the Scripps Research Institute. He returned to Japan in 1991 and continued his immunology research as the Head of the Department of Immunopathology at Tokyo Metropolitan Institute of Gerontology, Tokyo. From 1998 to 2011, he was a Professor of Institute for Frontier Medical Sciences Kyoto University and served as the Director of the Institute for several years. In 2011, his lab moved to Osaka University. He was awarded the Medal with Purple Ribbon from the Emperor in 2009, elected to Foreign Member of National Academy of Sciences USA in 2012, and has been awarded with many international prizes including Cancer Research Institute’s William B. Coley Award for Basic Immunology and Tumor Immunology in 2004, Keio Medical Science Prize in 2008, Canada Gairdner International Award in 2015 and the Crafoord Prize in 2017.